Polyethylenimine, Linear (MW 25000)

Biological Activity

Polyethylenimine Linear (PEI) solution consists of a cationic polymer transfection reagent with a molecular weight of 25,000, which forms a complex with nucleic acids and allows the complex to enter mammalian cells. In addition, Polyethylenimine Linear is one of the most commonly used reagents in small to large scale transfection.

Chemical Information

Molecular Weight	25000
Formula	(CH2CH2NH)N
CAS Number	26913-06-4
Form	Solid
Storage	2-8℃

References

[1] Jie Wang et al. Viruses. The 40 kDa Linear Polyethylenimine Inhibits Porcine Reproductive and Respiratory Syndrome Virus Infection by Blocking Its Attachment to Permissive Cells

[2] Jason T Rodier et al. J Ocul Pharmacol Ther. Linear Polyethylenimine-DNA Nanoconstruct for Corneal Gene Delivery

[3] Han Zhou et al. Mol Med Rep. Linear polyethylenimine-plasmid DNA nanoparticles are ototoxic to the cultured sensory epithelium of neonatal mice

[4] Chittimalla Chandrashekhar et al. Acta Biomater. Oligobenzylethylenimine enriches linear polyethylenimine with a pH-sensitive membrane-disruptive property and leads to enhanced gene delivery activity

[5] Paola Vicennati et al. Curr Med Chem. Polyethylenimine in medicinal chemistry