tPA antibody
Référence GTX79621-1mg
Conditionnement : 1mg
Marque : GeneTex
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Téléphone : +1 850 650 7790
Host | Sheep |
|---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | WB, ELISA |
Reactivity | Mouse, Rat |
| Package | 1 mg |
Datasheet File View product citations for antibody GTX79621 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| WB | Assay dependent |
| ELISA | Assay dependent |
Not tested in other applications.
Calculated MW
63 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
10 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Mouse
Immunogen
Recombinant full length wild-type mouse protein (Glycosylated).
Purification
Protein G purified
From serum
From serum
Conjugation
Unconjugated
RRID
AB_11172852
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Cellular Localization
Secreted,Extracellular space
Background
This gene encodes a key enzyme of the fibrinolytic pathway. The encoded protein undergoes proteolytic processing by plasmin to generate a heterodimeric serine protease that cleaves the proenzyme plasminogen to produce plasmin, a protease that is required to break down fibrin clots. Additionally, the encoded protein is involved in other biological processes such as synaptic plasticity, cell migration and tissue remodeling. Mice lacking the encoded protein display a reduction in long-term potentiation in hippocampus and conversely, transgenic mice overexpressing the encoded protein have increased and prolonged long-term potentiation. [provided by RefSeq, Jul 2015]