Ac4GalNAz [653600-56-7]
Referência CLK-1086-5
Tamanho : 5mg
Marca : Jena Bioscience
Contactar o distribuidor local :
Telefone : +1 850 650 7790
N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz)
For general laboratory use.
Shipping: shipped at ambient temperature
Storage Conditions: store at -20 °C
Shelf Life: 12 months after date of delivery
Molecular Formula: C16H22N4O10
Molecular Weight: 430.37 g/mol
Exact Mass: 430.13 g/mol
CAS#: 653600-56-7
Purity: mass identification (ESI-MS)
Form: amorphous solid
Color: off-white to grey
Solubility: DMSO, DMF, MeOH
Applications:
Glycoconjugate synthesis monitoring by metabolic labeling
Description:
The tetraacetylated N-Azidoacetyl-galactosamine (Ac4GalNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylgalactosamine(GalNAc).
The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.
Recommended concentration for metabolic labeling: 25-75 μM. This concentration range may serve as a starting point for an individual assay set-up.
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