Anti-CD2 Monoclonal Antibody (Clone:TS1/8)-Low Endotoxin
Anti-CD2 Monoclonal Antibody (Clone:TS1/8)-Low Endotoxin
Referência 30-1654-0.1
Tamanho : 0,1mg
Marca : Abeomics
Contactar o distribuidor local :
Telefone : +1 850 650 7790
| Format : | Low Endotoxin |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD2 (also known as LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Flow Cytometry Functional Application blocking
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| BioGrid: | 107352. 16 interactions. |
| There are currently no product reviews |
