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> Anti-CYP2A6 antibody (1-50 aa)

Anti-CYP2A6 antibody (1-50 aa)

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Referência NB-22-2568-50

Tamanho : 50ug

Marca : Neo Biotech

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Telefone : +1 850 650 7790

  • Western blot analysis of lysates from Jurkat cells, using Cytochrome P450 2A6 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from RAW264.7cells using CDH11 antibody.
  • Western blot analysis of PC-12 cells using CYP2A6 Polyclonal Antibody diluted at 1：1000

General Info

Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Rat/Mouse/Chicken
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cytochrome P450 2A6 (1-50 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: CYP2A6
Gene ID: 1548
Uniprot ID: CP2A6_HUMAN
Immunogen Region: 1-50 aa
Specificity: CYP2A6 Polyclonal Antibody detects endogenous levels of CYP2A6 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Cytochrome P450 2A6 at the amino acid range 1-50

Description

Function Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.
Protein Name Cytochrome P450 2a6
1 -4-Cineole 2-Exo-Monooxygenase
Cypiia6
Coumarin 7-Hydroxylase
Cytochrome P450 Iia3
Cytochrome P450(I
Database Links Reactome: R-HSA-211981
Reactome: R-HSA-211999
Cellular Localisation Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Microsome Membrane
Alternative Antibody Names Anti-Cytochrome P450 2a6 antibody
Anti-1 -4-Cineole 2-Exo-Monooxygenase antibody
Anti-Cypiia6 antibody
Anti-Coumarin 7-Hydroxylase antibody
Anti-Cytochrome P450 Iia3 antibody
Anti-Cytochrome P450(I antibody
Anti-CYP2A6 antibody
Anti-CYP2A3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance