General Info
| Host: | Rat |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Rat monoclonal antibody anti-Immunoglobulin heavy constant mu is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | RMM-1 |
| Conjugation: | AF647 |
| Isotype: | IgG2ak |
| Formulation: | PBS with 0.05% Proclin300, 1% BSA |
| Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Information
| Gene Symbol: | IghmUniprot ID=IGHM_MOUSE" |
Description
| Tissue Specificity | Mu' chain is expressed in bone marrow. |
| Post Translational Modifications | Cleaved by a non-enzymatic process after Asn-96, yielding a glycosylated protein of 55 kDa. The process is induced by other proteins, and requires neutral or alkaline pH. |
| Function | IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. |
| Protein Name | Immunoglobulin Heavy Constant Mu Cleaved Into - Mu' Chain55 Kda Mu' Chain |
| Cellular Localisation | Isoform 1: SecretedDuring DifferentiationB-Lymphocytes Switch From Expression Of Membrane-Bound Igm To Secretion Of IgmIsoform 2: Cell MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Immunoglobulin Heavy Constant Mu Cleaved Into - Mu' Chain antibodyAnti-55 Kda Mu' Chain antibodyAnti-Ighm antibodyAnti-Igh-6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance