Anti-iNOS Antibody
Referência OAAI00215
Tamanho : 100ug
Marca : Aviva Systems Biology
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Anti-iNOS Antibody (OAAI00215)
| Datasheets/Manuals | Printable datasheet for Anti-iNOS Antibody (OAAI00215) |
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| Predicted Species Reactivity | Human|Mouse|Rat |
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| Product Format | Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Application | ELISA, FC, IHC, IP, WB |
| Additional Information | Background: NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Notric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti-tumor and anti-pathogenic activities. Inducible NOS (iNOS) or macrophage NOS (mNOS) is a calcium/calmodulin independent and is expressed in activated macrophages and stimulated glial cells. |
| :: | Positive Control: Lung Tissue |
| :: | Cellular Location: Cytoplasmic |
| Reconstitution and Storage | The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles. |
| Immunogen | A synthetic peptide derived from C-term of iNOS protein |
| Purification | Affinity Purified |
| Concentration | 100ug/200ul |
| Specificity | NOS2 |
| Formulation | This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer |
| Application Info | WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested |
| Reference | Pawel J. Kolodziejski, et al. Ubiquitination of inducible nitric oxide synthase is required for its degradation. PNAS (2002) 99 (19), 12315-12320. |
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| Gene Symbol | NOS2 |
| Gene Full Name | nitric oxide synthase 2 |
| Alias Symbols | hepatocyte NOS;HEP-NOS;inducible NO synthase;inducible NOS;INOS;nitric oxide synthase 2, inducible;nitric oxide synthase 2A (inducible, hepatocytes);nitric oxide synthase, inducible;nitric oxide synthase, macrophage;NOS;NOS, type II;NOS2A;peptidyl-cysteine S-nitrosylase NOS2. |
| NCBI Gene Id | 4843 |
| Description of Target | NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Notric oxide thus geneRated acts as a messenger in diverse functions including vasodilation neurotransmission, anti-tumor and anti-pathogenic activities. Inducible NOS (iNOS) or macrophage NOS (mNOS) is a calcium/calmodulin independent and is expressed in activated macrophages and stimulated glial cells. |
| Uniprot ID | P35228 |
| Molecular Weight | 130 |
