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> Anti-WNT1 antibody (Clone: 10C8)

Anti-WNT1 antibody (Clone: 10C8)

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Referência NB-22-8549-50

Tamanho : 50ug

Marca : Neo Biotech

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  • Flow cytometric analysis of Hela cells using Wnt-1 monoclonal antibody (green) and negative control (purple).
  • Immunohistochemistry analysis of paraffin-embedded human LAdrenal tissues with AEC staining using Wnt-1 monoclonal antibody.
  • Confocal immunofluorescence analysis of Hela (left) and 3T3-L1 (right) cells using Wnt-1 monoclonal antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
  • Western blot analysis using Wnt-1 monoclonal antibody against NIH/3T3 (1) , 3T3L1 (2) and HeLa (3) cell lysate.

General Info

Host: Mouse
Applications: WB/IHC/IF/FC/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Proto-oncogene Wnt-1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications.
Clonality: Monoclonal
Clone ID: 10C8
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: WNT1
Gene ID: 7471
Uniprot ID: WNT1_HUMAN
Specificity: Wnt-1 Monoclonal Antibody detects endogenous levels of Wnt-1 protein.
Immunogen: Purified recombinant fragment of Wnt-1 expressed in E. Coli.

Description

Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.
Protein Name Proto-Oncogene Wnt-1
Proto-Oncogene Int-1 Homolog
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-3238698
Reactome: R-HSA-373080
Reactome: R-HSA-381340
Reactome: R-HSA-4086400
Reactome: R-HSA-4641262
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Proto-Oncogene Wnt-1 antibody
Anti-Proto-Oncogene Int-1 Homolog antibody
Anti-WNT1 antibody
Anti-INT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance