beta Actin (ACTB) Mouse Monoclonal Antibody [Clone ID: 10B7]

Specifications

Product Data
Clone Name	10B7
Applications	WB
Recommended Dilution	WB: 0.5-1µ/ml.
Reactivities	Human, Mouse, Rat, Rabbit, Chicken, Zebrafish, Drosophila
Host	Mouse
Isotype	IgG
Clonality	Monoclonal
Immunogen	beta-Actin antibody was raised against a synthetic peptide containing 16 amino acids near the carboxy terminus of beta-actin.
Formulation	beta-Actin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	beta-Actin Antibody is affinity chromatography purified via peptide column.
Conjugation	Biotin
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Predicted Protein Size	Predicted: 42 kDa; Observed: 42 kDa
Gene Name	actin, beta
Database Link	AAH02409 Entrez Gene 60 Human UniProt ID P60709
Background	Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. Beta actin is one of six different actin isoforms which have been identified. Like GAPDH, beta-Actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Synonyms	Beta-actin; PS1TP5BP1
Note	beta-Actin antibody can be used for detection of Beta-Actin by Western blot at 0.5 - 1 µ/ml.
Reference Data