C5 antibody
Referência GTX28789-1ml
Tamanho : 1ml
Marca : GeneTex
Host | Sheep |
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Clonality | Polyclonal |
Isotype | IgG |
Application | Immunodiffusion |
Reactivity | Human |
Package | 1 ml |
View product citations for antibody GTX28789 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
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Immunodiffusion | Assay dependent |
Not tested in other applications.
Calculated MW
188 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
Glycine buffered saline, 0.1% E-amino-n-caproic acid (EACA), 0.01% Benzamidine, 1mM EDTA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human C5, purified from plasma.
Purification
Purified by ion exchange chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
complement C5 , C5D , C5a , C5b , CPAMD4 , ECLZB
Cellular Localization
Secreted
Background
This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Database
REVIEW
SDS | |
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Sodium Azide.pdf |