Camostat Mesilate
Referência M2487-10mg
Tamanho : 10mg
Marca : AbMole Bioscience
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All AbMole products are for research use only, cannot be used for human consumption.
FOY-305; Camostat mesylate; FOY-S980
Quality Control & Documentation
Biological Activity
Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
Chemical Information
| Molecular Weight | 494.52 |
| Formula | C20H22N4O5.CH4O3S |
| CAS Number | 59721-29-8 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Serap Şimşek-Yavuz, et al. An update of anti-viral treatment of COVID-19
[2] Peter Breining, et al. Camostat mesylate against SARS-CoV-2 and COVID-19-Rationale, dosing and safety
[3] Dwight L McKee, et al. Candidate drugs against SARS-CoV-2 and COVID-19
[4] Yoshiharu Uno. Camostat mesilate therapy for COVID-19
[5] Markus Hoffmann, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor