CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: Psel.KO.2.7]
Referência SM2261R
Tamanho : 100Tests
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CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: Psel.KO.2.7]
SKU
SM2261R
CD62P (SELP) mouse monoclonal antibody, clone Psel.KO.2.7, PE
| Product Data | |
| Clone Name | Psel.KO.2.7 |
|---|---|
| Application | FC |
| Application | Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 106 cells in 100 µl. |
| Reactivity | Bovine, Equine, Feline, Goat, Human, Mouse, Rat, Sheep |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | P-selectin transfected 300.19 cells. |
| Specificity | This antibody recognises the CD62P cell surface antigen, a 140kD glycoprotein also known as P-Selectin. |
| Buffer | PBS, pH 7.4 Label: PE State: Lyophilized purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) Absorption emission: 488nm / 575nm |
| Reconstitution Method | Restore with 1.0 ml distilled water |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | PE |
| Storage | Store the antibody undiluted Prior to and After reconstitution at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Stability | Shelf life: One year from despatch. |
| Gene Name | selectin P |
| Database Link | |
| Background | CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster |
| Synonyms | SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.