CD81 antibody [1D6] (FITC)

Referência GTX75435-100ug

Tamanho : 100ug

Marca : GeneTex

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Anti-CD81 antibody [1D6] (FITC) used in Flow cytometry (FACS). GTX75435

Host

Mouse

Clonality

Monoclonal

Clone Name

1D6

Isotype

IgG1

Application

FACS

Reactivity

Human, Goat, Sheep, Chimpanzee
Package
100 μg
View product citations for antibody GTX75435 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

OCI-LY8 cells aggregated by CD81 antibody[5A6]

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Fluorescein isothiocyanate (FITC) Wavelength

RRID

AB_376798

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD81 molecule , CVID6 , S5.7 , TAPA1 , TSPAN28

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Database

DATA IMAGES

Anti-CD81 antibody [1D6] (FITC) used in Flow cytometry (FACS). GTX75435

GTX75435 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX75435 CD81 antibody [1D6] (FITC).

Clone Reference

Kateryna Nesteruk et al. Clin Transl Gastroenterol 2022; 13 (3):e00465 Size and Concentration of Extracellular Vesicles in Pancreatic Juice From Patients With Pancreatic Ductal Adenocarcinoma.
Stella Chin-Shaw Tsai et al. Int J Mol Sci 2021; 22 (13)
Clerici SP et al. Front Cell Dev Biol 2021; 9:696373 Colorectal Cancer Cell-Derived Small Extracellular Vesicles Educate Human Fibroblasts to Stimulate Migratory Capacity.
Mirzapoiazova T et al. Int J Cell Biol 2015; 2015:481493 Extracellular Vesicles from Caveolin-Enriched Microdomains Regulate Hyaluronan-Mediated Sustained Vascular Integrity.
Yamashita T et al. Pharmazie 2013; 68 (12):969-73 Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis.

REVIEW

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Clone Reference
Kateryna Nesteruk et al. Clin Transl Gastroenterol 2022; 13 (3):e00465 Size and Concentration of Extracellular Vesicles in Pancreatic Juice From Patients With Pancreatic Ductal Adenocarcinoma.
Stella Chin-Shaw Tsai et al. Int J Mol Sci 2021; 22 (13)
Clerici SP et al. Front Cell Dev Biol 2021; 9:696373 Colorectal Cancer Cell-Derived Small Extracellular Vesicles Educate Human Fibroblasts to Stimulate Migratory Capacity.
Mirzapoiazova T et al. Int J Cell Biol 2015; 2015:481493 Extracellular Vesicles from Caveolin-Enriched Microdomains Regulate Hyaluronan-Mediated Sustained Vascular Integrity.
Yamashita T et al. Pharmazie 2013; 68 (12):969-73 Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis.
SDS
PBS.pdf
Sodium Azide.pdf