CFTR/MRP, (ATP-Binding Cassette, sub-family C, Member 13, PRED6, ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene)

Referência C9040-01B-100ug

Tamanho : 100ug

Marca : US Biological

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C9040-01B CFTR/MRP, (ATP-Binding Cassette, sub-family C, Member 13, PRED6, ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene)

Clone Type
Polyclonal
Host
goat
Source
human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
AAL47201.1; AAQ22368.1; EAX10059.1
Shipping Temp
Blue Ice
Storage Temp
-20°C

This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described.||Applications:|Suitable for use in ELISA. Other applications have not been tested. ||Recommended Dilutions: |Peptide ELISA Titer: 1:128,000|Optimal dilutions to be determined by the researcher. ||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: goat|Source: human|Concentration: ~0.5mg/ml|Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.|Purity: Purified by peptide affinity chromatography.|Immunogen: Synthetic peptide corresponding to CEHSSDFGWNGY, from the internal region of human CFTR/MRP. |Species Sequence Homology: canine|Specificity: Recognizes human CFTR/MRP. ||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic peptide corresponding to CEHSSDFGWNGY, from the internal region of human CFTR/MRP. |Species Sequence Homology: canine
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by peptide affinity chromatography.
Specificity
Recognizes human CFTR/MRP.
References
1. Yabuuchi H, Takayanagi S, Yoshinaga K, Taniguchi N, Aburatani H, Ishikawa T ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver Biochem Biophys Res Commun. 2002 Dec 6;299(3):410-7