Colchicine cryst., research grade

Referência 77120.03

Tamanho : 5G

Marca : SERVA Electrophoresis

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C22H25NO6Mr 399.44CAS [64-86-8]

Colchicine inhibits microtubule polymerization by binding to tubulin, which disrupts spindle formation during mitosis. Since increased rate of mitosis is associated with cancer cell proliferation, blocking microtubule function with colchicine has been used as an approach to anti-cancer therapy. Its mitosis-inhibiting function is also utilized to perform karyotypes in genetic studies.
Colchicine blocks chromosome segregation during meiosis. Therefore it is used to induce polyploidy (tetraploid) in plant cells.



Assay (HPLC)
94.0 - 101.0 %

DANGER
Hazard Statements H300 - H340
Precautions P201 - P280
Reaction P301 +P310 - P308 +P313 - P330
Storage P405

Muta. 1BEG-Index: 614-005-00-6GGVSE/ADR: 6.1 II UN1544IATA: 6.1 II UN1544EINECS: 200-598-5WGK: 3LHS: 29397990
Storage Temperature: +15 °C to +30 °C

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A3324-250mg
 250mg