Cyclooxygenase 2 Polyclonal Antibody, PE-Cy5 Conjugated

Referência bs-10411R-PE-Cy5

Tamanho : 100ul

Marca : Bioss

Solicitar mais informações

Contactar o distribuidor local :


Telefone : +1 850 650 7790

Cyclooxygenase 2 Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat
  • Sheep

Predicted Reactivity

  • Dog
  • Cow
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-10411R-PE-Cy5
Product Name Cyclooxygenase 2 Polyclonal Antibody, PE-Cy5 Conjugated
Applications WB
Reactivity Human, Mouse, Rat, Sheep
Predicted Reactivity Dog, Cow, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Cyclooxygenase 2
Immunogen Range 301-400/604
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5743
Swiss Prot P35354
Subcellular location Cytoplasm
Synonyms COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS; Prostaglandin G/H synthase 2; Cyclooxygenase-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; Prostaglandin-endoperoxide synthase 2; PTGS2
Background Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Application Dilution
WB 1:300-5000