DNA Gyrase from E. coli

Product Description

DNA Gyrase from E. coli
Catalog number: B2012999
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 Units
Molecular Weight or Concentration: 374 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: DNA Gyrase from Escherichia coli
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Vanden Broeck A, Lotz C, Ortiz J, Lamour V. Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex Nat Commun. 2019 Oct 30;10(1):4935.
2: Fernández-Sierra M, Shao Q, Fountain C, Finzi L, Dunlap D. E. coli Gyrase_ Fails to Negatively Supercoil Diaminopurine-Substituted DNA J Mol Biol. 2015 Jul 3;427(13):2305-18.
3: Munir S, Khurshid M, Ahmad M, Ashfaq UA, Zaki MEA. Exploring the Antimicrobial and Pharmacological Potential of NF22 as a Potent Inhibitor of E._coli DNA_Gyrase: An In Vitro and In Silico Study Pharmaceutics. 2022 Dec 10;14(12):2768.
4: Duprey A, Groisman EA. DNA supercoiling differences in bacteria result from disparate DNA_gyrase activation by polyamines PLoS Genet. 2020 Oct 30;16(10):e1009085.
5: Shiriaev DI, Sofronova AA, Berdnikovich EA, Lukianov DA, Komarova ES, Marina VI, Zakalyukina YV, Biryukov MV, Maviza TP, Ivanenkov YA, Sergiev PV, Osterman IA, Dontsova OA. Nybomycin inhibits both types of E. coli DNA gyrase – fluoroquinolone-sensitive and fluoroquinolone-resistant Antimicrob Agents Chemother. 2021 Feb 16;65(5):e00777-20.
6: Brown PO, Peebles CL, Cozzarelli NR. A topoisomerase from Escherichia_coli related to DNA_gyrase Proc Natl Acad Sci U S A. 1979 Dec;76(12):6110-4.
7: Fois B, Skok Ž, Tomašič T, Ilaš J, Zidar N, Zega A, Peterlin Mašič L, Szili P, Draskovits G, Nyerges Á, Pál C, Kikelj D. Dual Escherichia coli DNA_Gyrase A and B Inhibitors with Antibacterial Activity ChemMedChem. 2020 Feb 5;15(3):265-269.
8: Stracy M, Wollman AJM, Kaja E, Gapinski J, Lee JE, Leek VA, McKie SJ, Mitchenall LA, Maxwell A, Sherratt DJ, Leake MC, Zawadzki P. Single-molecule imaging of DNA_gyrase activity in living Escherichia coli Nucleic Acids Res. 2019 Jan 10;47(1):210-220.
9: Morrison A, Cozzarelli NR. Site-specific cleavage of DNA by E. coli_DNA_gyrase Cell. 1979 May;17(1):175-84.
10: Shilpakala SR, Raghunathan M. Impact of DNA gyrase inhibition by antisense ribozymes on rec A in E. coli Mol Biol Rep. 2009 Sep;36(7):1937-42.

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