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Epothilone B [152044-54-7]
Referência 10-2133-5mg
Tamanho : 5mg
Marca : Focus Biomolecules
Contactar o distribuidor local :
Telefone : +1 850 650 7790
Epothilone B | Microtubule stabilizing agent
CAS:
152044-54-7
Catalog Number:
10-2133
Activity:
Microtubule stabilizing agent
Alternate Names:
EPO-906; EpoBI, Patupilone
Molecular Weight:
507.69
Molecular Formula:
C27H41NO6S
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT
Epothilone B (152044-54-7) induces microtubule polymerization. Causes cell cycle arrest at the G2-M transition (EC50 = 32 nM for HeLa cells). Induces apoptosis. Cell permeable.
References/Citations:
1) Goodin et al. (2004), Epothilones: mechanism of action and biologic activity; J. Clin. Oncol., 22 2015
2) Bollag et al. (1995), Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action; Cancer Res., 55 2325
CAS:
152044-54-7
Catalog Number:
10-2133
Activity:
Microtubule stabilizing agent
Alternate Names:
EPO-906; EpoBI, Patupilone
Molecular Weight:
507.69
Molecular Formula:
C27H41NO6S
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT
Safety Data Sheet:
N/A
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee
Epothilone B (152044-54-7) induces microtubule polymerization. Causes cell cycle arrest at the G2-M transition (EC50 = 32 nM for HeLa cells). Induces apoptosis. Cell permeable.
References/Citations:
1) Goodin et al. (2004), Epothilones: mechanism of action and biologic activity; J. Clin. Oncol., 22 2015
2) Bollag et al. (1995), Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action; Cancer Res., 55 2325
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