FUNDC1 antibody - N-terminal region
Referência ARP53280_P050
Tamanho : 100ul
Marca : Aviva Systems Biology
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FUNDC1 Antibody - N-terminal region (ARP53280_P050)
| Datasheets/Manuals | Printable datasheet for anti-FUNDC1 (ARP53280_P050) antibody |
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| Publications | BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation. Autophagy. , 42370 (2020). 33044904 FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions. EMBO J. 35, 1368-84 (2016). 27145933 Huang, M. L.-H. et al. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2a phosphorylation, and the induction of downstream targets. Am. J. Pathol. 183, 745-57 (2013). 23886890 | ||||||
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| Tested Species Reactivity | Human | ||||||
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | ||||||
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | ||||||
| Clonality | Polyclonal | ||||||
| Host | Rabbit | ||||||
| Application | WB, IP | ||||||
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. | ||||||
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human FUNDC1 | ||||||
| Purification | Affinity Purified | ||||||
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% | ||||||
| Peptide Sequence | Synthetic peptide located within the following region: MATRNPPPQDYESDDDSYEVLDLTEYARRHQWWNRVFGHSSGPMVEKYSV | ||||||
| Concentration | 0.5 mg/ml | ||||||
| Blocking Peptide | For anti-FUNDC1 (ARP53280_P050) antibody is Catalog # AAP53280 (Previous Catalog # AAPP30762) | ||||||
| Enhanced Validation |
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| Reference | Ross,M.T., (2005) Nature 434 (7031), 325-337 |
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| Gene Symbol | FUNDC1 |
| Gene Full Name | FUN14 domain containing 1 |
| Alias Symbols | MGC51029 |
| NCBI Gene Id | 139341 |
| Protein Name | FUN14 domain-containing protein 1 |
| Description of Target | FUNDC1 belongs to the FUN14 family. The exact function of FUNDC1 remains unknown. |
| Uniprot ID | Q8IVP5 |
| Protein Accession # | NP_776155 |
| Nucleotide Accession # | NM_173794 |
| Protein Size (# AA) | 155 |
| Molecular Weight | 17 kDa |
| Protein Interactions | SLC25A46; MAP1LC3A; MAP1LC3B; SENP2; SH3GLB1; MTERF3; GABARAPL1; GABARAPL2; YES1; TUFM; SNX1; EHHADH; CTBP2; CTBP1; UBC; |
