Giantin (Recombinant) (Golgin Subfamily B Member 1, 372 D Golgi Complex-associated Protein, GCP372, Macrogolgin)

Referência 044839-100ug

Tamanho : 100ug

Marca : US Biological

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044839 Giantin (Recombinant) (Golgin Subfamily B Member 1, 372 D Golgi Complex-associated Protein, GCP372, Macrogolgin)

Clone Type
Polyclonal
Host
human
Source
human
Isotype
IgG2
Grade
Purified
Applications
IC
Crossreactivity
Hu Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C

Giantin, the largest Golgi membrane protein, is C-terminally anchored to cis- and medial-Golgi membranes and forms a long ~250nm coiled-coil rod that directly interacts with microtubules in a cell-cycle regulated way. It is an excellent marker for mammalian golgi complex. It is also an antigen in chronic rheumatoid arthritis and in the autoimmune disease Sjoegren syndrome.||Applications:|Suitable for use in Immunocytochemistry. Other applications not tested.||Recommended Dilutions:|Immunocytochemistry: 1:1000|Optimal dilutions to be determined by researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgG2|Clone No: TA10|Host: human|Source: human|Concentration: ~1mg/ml|Form: Supplied as a liquid in PBS, 0.02% sodium azide, 10% glycerol|Purity: Purified|Immunogen: Recombinant protein corresponding to human giantin|Specificity: Recognizes human giantin. Species Crossreactivity: mouse||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant protein corresponding to human giantin
Form
Supplied as a liquid in PBS, 0.02% sodium azide, 10% glycerol
Purity
Purified
Specificity
Recognizes human giantin. Species Crossreactivity: mouse
References
1. Recombinant antibodies selected against subcellular fractions to track endogenous protein dynamics in vivo: C. Nizak, et al.; Traffic 7, 739 (2003) 2. Characterization of single chain antibody targets through yeast two hybrid: O. Vielemeyer, et al; BMC Biotechnol. 10, 59 (2010).