GLDC Antibody : FITC
Referência ARP54297_P050-FITC
Tamanho : 100ul
Marca : Aviva Systems Biology
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GLDC Antibody (ARP54297_P050)
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| Datasheets/Manuals | Printable datasheet for anti-GLDC (ARP54297_P050) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the following sequence LENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGT |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: LENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGT |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | Available upon request |
| Gene Symbol | GLDC |
|---|---|
| Gene Full Name | glycine dehydrogenase (decarboxylating) |
| Alias Symbols | GCE, GCSP, HYGN1 |
| NCBI Gene Id | 2731 |
| Protein Name | Glycine dehydrogenase [decarboxylating], mitochondrial |
| Description of Target | Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). |
| Uniprot ID | P23378 |
| Protein Accession # | NP_000161 |
| Nucleotide Accession # | NM_000170 |
| Protein Size (# AA) | 1,020 |
| Molecular Weight | 113 kDa |
| Protein Interactions | SUZ12; UBC; CUL2; TNFAIP3; TLR10; GLDC; |
