Glyco-Obeticholic Acid (Highly Pure)
Catalog Number: B2012720 (1 mg)
Glyco-Obeticholic Acid (Highly Pure) is a high quality active metabolite of obeticholic acid and semisynthetic derivative of chenodeoxycholic acid. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
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Product Description
Glyco-Obeticholic Acid (Highly Pure)
Catalog number: B2012720
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 477.7 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Obeticholic Acid Glycine Conjugate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Ratziu V. Obeticholic Acid for the Treatment of Nonalcoholic Steatohepatitis Clin Liver Dis (Hoboken). 2021 Aug 5;17(6):398-400.
2: Aust Prescr. 2020 Oct;43(5):174-175. doi: 10.18773/austprescr.2020.063. Epub 2020 Oct 1. Obeticholic acid for primary biliary cholangitis Aust Prescr
3: Abdelmalek MF. Nonalcoholic fatty liver disease: another leap forward Nat Rev Gastroenterol Hepatol. 2021 Feb;18(2):85-86.
4: Rinella ME, Dufour JF, Anstee QM, Goodman Z, Younossi Z, Harrison SA, Loomba R, Sanyal AJ, Bonacci M, Trylesinski A, Natha M, Shringarpure R, Granston T, Venugopal A, Ratziu V. Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study J Hepatol. 2022 Mar;76(3):536-548.
5: Manne V, Kowdley KV. Obeticholic acid in primary biliary cholangitis: where we stand Curr Opin Gastroenterol. 2019 May;35(3):191-196.
6: Polyzos SA, Kountouras J, Mantzoros CS. Obeticholic acid for the treatment of nonalcoholic steatohepatitis: Expectations and concerns Metabolism. 2020 Mar;104:154144.
7: Markham A, Keam SJ. Obeticholic Acid: First Global Approval Drugs. 2016 Aug;76(12):1221-6.
8: Fiorucci S, Di Giorgio C, Distrutti E. Obeticholic Acid: An Update of Its Pharmacological Activities in Liver Disorders Handb Exp Pharmacol. 2019;256:283-295.
9: Roy PP, Mahtab MA, Rahim MA, Yesmin SS, Islam SB, Akbar SMF. Treatment of Nonalcoholic Steatohepatitis by Obeticholic Acid: Current Status Euroasian J Hepatogastroenterol. 2022 Jul;12(Suppl 1):S46-S50.
10: Kjærgaard K, Frisch K, Sørensen M, Munk OL, Hofmann AF, Horsager J, Schacht AC, Erickson M, Shapiro D, Keiding S. Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis J Hepatol. 2021 Jan;74(1):58-65.
Products Related to Glyco-Obeticholic Acid (Highly Pure) can be found at Chemicals
Additional Information
| Weight | 48 oz |
|---|---|
| Dimensions | 8 × 8 × 8 in |