Human Cortisol ELISA kit
Referência EA100853
Tamanho : 1x96wells
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Human Cortisol ELISA kit
| Product Data | |
| Assay Length | 3 hours |
|---|---|
| Assay Platform | 96-well plate |
| Assay Type | Streptavidin based ELISA |
| Assay Type | Sandwich |
| Background | Cortisol (hydrocortisone, compound F) is the most potent glucocorticoid synthesized from cholesterol. Cortisol is found in the blood either as free Cortisol, or bound to corticosteroid-binding globulin (CBG). Cortisol production has an ACTH- dependent circadian rhythm with peak levels in the early morning and a nadir at night. The factors controlling this circadian rhythm are not completely defined. Serum levels are highest in the early morning and decrease throughout the day. In the metabolic aspect, Cortisol promotes gluconeogenesis, liver glycogen deposition, and the reduction of glucose utilization. Immunologically, Cortisol functions as an important anti inflammatory, and plays a role in hypersensitivity, immunosuppression, and disease resistance. It has also been shown that plasma Cortisol levels elevate in response to stress. Abnormal Cortisol levels are seen with a variety of different conditions: with adrenal tumors, prostate cancer, depression, and schizophrenia. Elevated Cortisol levels and lack of diurnal variation have been identified in patients with Cushing's disease. |
| Components |
|
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Curve Range | 20-400 ng/ml |
| Format | 8x12 divisible strips |
| Interference | No significant interference observed with available related molecules. |
| Reactivity | Human |
| Reactivity | Human |
| Reactivity | Human |
| Sample Type | Serum |
| Sample Volume | 25 µl/well |
| Sensitivity | 20 ng/ml |
| Signal | Colorimetric |
| Species | Human |
| Specificity | This kit is used for quantitative detection human Cortisol |
| New | No |
| Description | Human Cortisol ELISA kit |