600345 | Human IFNa-2b Clinisciences

Recombinant Active Protein

Cat. No.

600345

Unit

0.1 mg

Description

Interferon-alpha 2b (IFNalpha 2b) is a Type I interferon made by leukocytes during viral infection. It has anti-viral and non-proliferative activity induced by JAK1-STAT signaling. IFN-alphas are the most widely used type for therapeutic purposes. IFN alpha 2b is a variant of IFN alpha 2a that differs by one amino acid. Human IFNa-2b is produced in E. coli. Recombinant human IFN alpha 2b is a non-glycosylated protein, containing 166 amino acids, with a molecular weight of 19.4 kDa.

Spec Container

Datasheet

Format

Each vial contains 100 ug of lyophilized protein. Reconstitute with 1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Alternate Names

IFN-alpha 2b; Interferon alpha-2; Interferon alpha-B; LeIF A; IFNA2

Accession No.

P01563

19400 Da

Sequence

MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Source

E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Purity

Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Application Notes

The activity can be determined by the ability to induce antiviral activity. There is no biological assay data available at this time.

Storage

Store at -20C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

Images

For research use only, not for diagnostic or therapeutic procedures.

Human IFNa-2b

Referência 600345

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Marca : Abbiotec

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Spec Container