Human Pancreatic Lipase (PNLIP) activation kit by CRISPRa
Referência GA103636
Tamanho : 1kit
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Human Pancreatic Lipase (PNLIP) activation kit by CRISPRa
SKU
GA103636
PNLIP CRISPRa kit - CRISPR gene activation of human pancreatic lipase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | PNLIP |
| Locus ID | 5406 |
| Components | GA103636G1, Pancreatic Lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103636G2, Pancreatic Lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103636G3, Pancreatic Lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000936 |
| UniProt ID | P16233 |
| Synonyms | PL; PNLIPD; PTL |
| Summary | This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea. [provided by RefSeq, Jul 2016] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN404735 | PNLIP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.