Human Proteasome 20S alpha 5 (PSMA5) activation kit by CRISPRa
Referência GA103855
Tamanho : 1kit
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Human Proteasome 20S alpha 5 (PSMA5) activation kit by CRISPRa
SKU
GA103855
PSMA5 CRISPRa kit - CRISPR gene activation of human proteasome subunit alpha 5
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | PSMA5 |
| Locus ID | 5686 |
| Components | GA103855G1, Proteasome 20S alpha 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103855G2, Proteasome 20S alpha 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103855G3, Proteasome 20S alpha 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001199772, NM_001199773, NM_001199774, NM_002790 |
| UniProt ID | P28066 |
| Synonyms | PSC5; ZETA |
| Summary | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN410717 | PSMA5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.