Human TP53 Antibody : APC (Phospho-Ser15)
Referência OAAQ00039-100tests
Tamanho : 100Tests
Marca : Aviva Systems Biology
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Human TP53 Antibody : APC (Phospho-Ser15) (OAAQ00039)
| Datasheets/Manuals | Printable datasheet for OAAQ00039 |
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| Tested Species Reactivity | Human, Mouse |
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| Predicted Species Reactivity | Mouse, Rat |
| Product Format | Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA. |
| Clonality | Monoclonal |
| Clone | P53S15-1C11 |
| Isotype | Rabbit IgG1k |
| Host | Rabbit |
| Conjugation | APC: Allophycocyanin |
| Application | FC |
| Reconstitution and Storage | 2-8C |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser15 of human phospho p53. |
| Purification | Protein A+G |
| Target Post-Translational Modification | Phospho-Ser15 |
| Application Info | For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application. |
| Reference | Vogelstein B, Lane D, and Levine AJ. (2000) Nature. 408: 307-310. |
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| Gene Symbol | TP53 |
| Gene Full Name | tumor protein p53 |
| Alias Symbols | P53, BCC7, LFS1, BMFS5, TRP53 |
| NCBI Gene Id | 7157 |
| Protein Name | cellular tumor antigen p53 |
| Description of Target | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
| Uniprot ID | P04637 |
| Protein Accession # | NP_000537.3 |
| Nucleotide Accession # | NM_000546.5 |
