IRS-1(Ser307) Polyclonal Antibody, HRP Conjugated
Referência bs-2736R-HRP
Tamanho : 100ul
Marca : Bioss
IRS-1(Ser307) Polyclonal Antibody, HRP Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-2736R-HRP |
Product Name | IRS-1(Ser307) Polyclonal Antibody, HRP Conjugated |
Applications | ELISA, IHC-P, IHC-F |
Specificity | This phosphorylation site is homologous to Ser302 in Mouse and Rat. |
Reactivity | Human, Mouse, Rat, Goat |
Predicted Reactivity | Dog, Cow, Pig, Horse, Rabbit |
Specifications | |
Conjugation | HRP |
Host | Rabbit |
Source | KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser307 [TE(p-S)IT] |
Modification Site | Ser307 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 3667 |
Swiss Prot | P35568 |
Subcellular location | Cell membrane |
Synonyms | HIRS-1; Insulin receptor substrate 1; IRS-1; IRS1 |
Background | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). |
Application Dilution | |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |