MADH7 (SMAD7) Rabbit Polyclonal Antibody

Referência TA322547

Tamanho : 100ul

Solicitar mais informações

Contactar o distribuidor local :


Telefone :

MADH7 (SMAD7) Rabbit Polyclonal Antibody

Specifications
Product Data
Application IHC
Application IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 370-383 amino acids of Human SMAD family member 7
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name SMAD family member 7
Database Link
Background The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding; this complex translocates to the cytoplasm; where it interacts with TGF-beta receptor type-1 (TGFBR1); leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
Synonyms CRCS3; MADH7; MADH8
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways TGF-beta signaling pathway
Write Your Own Review
You're reviewing:MADH7 (SMAD7) Rabbit Polyclonal Antibody
Your Rating
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Products

  • cDNA Clones
  • Antibodies
  • Proteins
  • Vectors
  • RNAi
  • Gene Expression
  • Assay Kits
  • Tissues
  • Others

Product Support

  • Product FAQs
  • Product Manuals
  • SDS
  • Citations

Customer Support

  • Order Support
  • Technical Support
  • International Distributors
  • cDNA Clone Match
  • Product Review

Learning Resources

  • Video and Webinar
  • Brochures & Flyers
  • Protocols
  • Ebooks
  • Scientific Papers
  • Bioinformatics Tools

About Us

  • About Us
  • Press Releases
  • Conferences
  • Customer Testimonials
  • Careers
  • Legal Notices
  • Contact Us

Você também pode estar interessado nos seguintes produtos:



Referência
Descrição
Cond.
Price Bef. VAT
TA313880
 100ul