MIA PaCa-2 cells
Referência C0018002
Tamanho : OneFrozenvial
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Disease:
Pancreatic carcinoma An established cell line from an undifferentiated human pancreatic carcinoma Homo sapiens Pancreas Epithelial Adherent, single cells and loosely attached clusters Tumorigenic; Modal no. 61; hypotriploid Male, Caucasian, 65 yrs of age AddexBio-formulated DMEM (C0003-01) + 10% FBS 1:3 to 1:6 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C Complete culture medium supplemented with 5% (v/v) DMSO Bacteria: Negative Yeast: Negative Mycoplasma: Negative HIV: Negative Hepatitis B: Negative Hepatitis C: Negative AR-42J cells BxPc-3 cells Capan-1 cells MIA PaCa-2 cells E3LZ10.7 cells A10.7 cells INS-1 cells MIN-6 cells Origin:
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Cytogenic data:
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Biosafety Level:
I Sterility:
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Protein Expression:
human colony stimulating factor, subclass I (CSF-I); plasminogen activator Isoenzymes:
G6PD, B DNA Profile (STR):
Amelogenin: X CSF1PO: 10 D13S317: 12,13 D16S539: 10,13 D5S818: 12,13 D7S820: 12,13 THO1: 9,10 TPOX: 9 vWA: 15 Related cells by Organ:
References for MIA PaCa-2 cells:
1. Hussein, D. and Mo, H. d-delta-Tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells. Pancreas, 38: e124-136, 2009.
2. Reigan, P., Colucci, M. A., Siegel, D., Chilloux, A., Moody, C. J., and Ross, D. Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells. Biochemistry, 46: 5941-5950, 2007.
3. Kato, S., Shirato, K., Imaizumi, K., Toyota, H., Mizuguchi, J., Odawara, M., Che, X. F., Akiyama, S., Abe, A., and Tomoda, A. Anticancer effects of phenoxazine derivatives combined with tumor necrosis factor-related apoptosis-inducing ligand on pancreatic cancer cell lines, KLM-1 and MIA-PaCa-2. Oncol Rep, 15: 843-848, 2006.
4. Fogli, S., Nieri, P., Chicca, A., Adinolfi, B., Mariotti, V., Iacopetti, P., Breschi, M. C., and Pellegrini, S. Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptor-independent mechanism. FEBS Lett, 580: 1733-1739, 2006.
5. Roomi, M. W., Ivanov, V., Kalinovsky, T., Niedzwiecki, A., and Rath, M. Antitumor effect of a combination of lysine, proline, arginine, ascorbic acid, and green tea extract on pancreatic cancer cell line MIA PaCa-2. Int J Gastrointest Cancer, 35: 97-102, 2005.
6. Hashimoto, K., Farrow, B. J., and Evers, B. M. Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2. Pancreas, 28: 153-159, 2004.