Conjugation | PerCP-Cyanine5.5 |
---|---|
Antigen | CD14 |
Clone | 26ic |
Isotype | IgG2b, k |
Applications | FC |
Reactivity | Baboon, Cynomolgus monkey, Human, Rhesus |
Host | Mouse |
Clonality | Monoclonal |
Primary/Secondary | Primary |
Storage | 2-8°C |
Status | RUO |
Excitation Laser | Blue (488nm) |
CD14 PerCP-Cyanine5.5
Catalog #
Size
Monocytes-gated PBMCs stained with CD14 (26ic) PerCP-Cyanine5.5 (RED); Monocytes -gated PBMCs stained with mouse IgG2b PerCP-Cyanine5.5 isotype control (BLUE).
Description:
The clone 26ic, a mouse monoclonal antibody, reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)- anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. 26ic binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.
The clone 26ic, a mouse monoclonal antibody, reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)- anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. 26ic binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.