Conjugation | PerCP |
---|---|
Antigen | CD8a |
Clone | SK1 |
Isotype | IgG1, k |
Applications | FC |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Primary/Secondary | Primary |
Immunogen | Human peripheral blood T lymphocytes |
Format | 0.09% sodium azide, 0.2% BSA (w/v), PBS pH 7.2 |
Storage | 2-8°C |
Status | RUO |
Excitation Laser | Blue (488nm) |
CD8a PerCP
Catalog #
Size
Description:
The clone SK1 specifically binds with a 32-34kDa type I transmembrane glycoprotein of human cells commonly known as CD8a. It is a member of immunoglobulin superfamily. The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.
The clone SK1 specifically binds with a 32-34kDa type I transmembrane glycoprotein of human cells commonly known as CD8a. It is a member of immunoglobulin superfamily. The CD8α forms either a homodimer (2 alpha chains) or a heterodimer with CD8β and is expressed on the surface of cytotoxic T cells, and sub-sets of NK cells, cortical thymocytes, and also on some dendritic cells. CD8 functions as a co-receptor for T cell receptor and specifically binds to class I MHC for antigen recognition and T cell activation. It has the cross-reactive binding affinity with the CD8 cell surface antigen expressing in several non-human primates, including Baboon, Chimpanzee, Cynomolgus and Rhesus.