Mouse Hdac6 activation kit by CRISPRa

Referência GA201864

Tamanho : 1kit

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Mouse Hdac6 activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Hdac6
Locus ID 15185
Components

GA201864G1, Hdac6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201864G2, Hdac6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201864G3, Hdac6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001130416, NM_010413
UniProt ID Q9Z2V5
Synonyms Hd6; Hdac5; mHDA2; Sfc6
Summary Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.[UniProtKB/Swiss-Prot Function]
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SKU Description Size
KN507621 Hdac6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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