Mouse Vldlr activation kit by CRISPRa

Referência GA204604

Tamanho : 1kit

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Mouse Vldlr activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vldlr
Locus ID 22359
Components

GA204604G1, Vldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204604G2, Vldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204604G3, Vldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001161420, NM_001347441, NM_013703
UniProt ID P98156
Synonyms AA408956; AI451093; AW047288
Summary Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.[UniProtKB/Swiss-Prot Function]
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SKU Description Size
KN518900 Vldlr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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