MQA-P (TFA)
Referência HY-149203A-1mg
Tamanho : 1mg
Marca : MedChemExpress
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO-, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images.
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MQA-P TFA Chemical Structure
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Based on 1 publication(s) in Google Scholar
Other Forms of MQA-P TFA:
- MQA-P Obtenir un devis
Description |
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO-, λem=645 nm; and NIR channel at λem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images[1][2]. |
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In Vitro |
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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In Vivo |
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Masse moléculaire |
720.72 |
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Formule |
C42H36F3N2O4P |
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Appearance |
Solid |
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Color |
Dark purple to black |
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SMILES |
O=C([O-])C(F)(F)F.CN(C1=CC=C(C=C1)/C=C/C=C/C2=CC=[N+](C3=C2C=CC=C3)CC4=CC=C(C=C4)OP(C5=CC=CC=C5)(C6=CC=CC=C6)=O)C |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Solvant et solubilité |
In Vitro:
DMSO : 10 mg/mL (13.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Pureté et documentation |
Purity: 97.36%
SDS (252 KB)
COA (253 KB) HNMR (155 KB) RP-HPLC (177 KB) LCMS (389 KB) Instruction de manipulation (2659 KB) |
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Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 1.3875 mL | 6.9375 mL | 13.8750 mL | 34.6875 mL |
5 mM | 0.2775 mL | 1.3875 mL | 2.7750 mL | 6.9375 mL | |
10 mM | 0.1388 mL | 0.6938 mL | 1.3875 mL | 3.4688 mL |
MQA-P TFA Related Classifications
- Others
- Others
- Fluorescent Dye
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
MQA-PFluorescent DyeInhibitorinhibitorinhibit