N-Glycolylneuraminic acid
Referência M19972-10mg
Tamanho : 10mg
Marca : AbMole Bioscience
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NeuGc; GcNeu
Quality Control & Documentation
Biological Activity
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).
Chemical Information
| Molecular Weight | 325.27 |
| Formula | C11H19NO10 |
| CAS Number | 1113-83-3 |
| Solubility (25°C) | Water ≥ 60 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Cindy M Spruit, et al. J Virol. N-Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses
[2] Renato Mastrangeli, et al. Trends Pharmacol Sci. Current views on N-glycolylneuraminic acid in therapeutic recombinant proteins
[3] Sharon Yehuda, et al. Front Immunol. Glycosylated Biotherapeutics: Immunological Effects of N-Glycolylneuraminic Acid
[4] Andrea Perota, et al. Front Immunol. N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)
[5] Anoopjit Singh Kooner, et al. Front Immunol. Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides