NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A) (MaxLight 550)

Referência 039006-ML550-100ul

Tamanho : 100ul

Marca : US Biological

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039006-ML550 Rabbit Anti-NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A) (MaxLight 550)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
P78426
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu
Accession #
NP_006159.2
Gene #
NKX6-1
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. ||In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM].||Applications:|Suitable for use in Western Blot, FLISA||Recommended Dilution:|FLISA: 1:1,000|Western Blot: 1:100-500||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.|Purity: Purified by Protein A affinity chromatography.|Immunogen: NKX6-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human NKX6-1.|Specificity: Human||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
NKX6-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human NKX6-1.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Donelan, W., et al. J. Biol. Chem. 285(16):12181-12189(2010)|Zhu, S., et al. Dig. Dis. Sci. 54(5):996-1002(2009)|Schisler, J.C., et al. Mol. Cell. Biol. 28(10):3465-3476(2008)|Yokoi, N., et al. Diabetes 55(8):2379-2386(2006)|Hori, Y., et al. PLoS Med. 2 (4), E103 (2005) :