Nr4a3 Mouse shRNA Lentiviral Particle (Locus ID 18124)

Referência TL501493V

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Nr4a3 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control) locus_ID:18124

Nr4a3 Mouse shRNA Lentiviral Particle (Locus ID 18124)

SKU
TL501493V
Nr4a3 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
  • Lenti

    Ready-to-use Lentiviral Particles

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2 Weeks*
Specifications
Product Data
Locus ID 18124
Synonyms AI573420; CHN; CSMF; M; MINOR; N; NO; NOR-1; Nor1; TEC
Vector pGFP-C-shLenti
Format Lentiviral particles
Components Nr4a3 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.
RefSeq NM_015743, NM_015743.1, NM_015743.2, NM_015743.3, BC038520, BC068150, BC128307, BC128308, BC148436, BC156736
UniProt ID Q9QZB6
Summary This gene encodes a member of the NR4A subfamily of nuclear hormone receptors that bind to DNA and modulate gene expression. The encoded protein has been implicated in T and B lymphocyte apoptosis, and immune cell proliferation. Mice lacking the encoded protein exhibit partial bidirectional circling behavior and inner ear dysfunction. Disruption of this gene in mice also results in defective hippocampal axonal growth and postnatal neuronal cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples.

For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at tech@clinisciences.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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