Phosal 50 PG [774594-96-6]

Referência HY-Y1903-25mL

Tamanho : 25mL

Marca : MedChemExpress

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Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient.

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Phosal 50 PG Chemical Structure

Phosal 50 PG Chemical Structure

CAS No. : 774594-96-6

This product is a controlled substance and not for sale in your territory.

Based on 4 publication(s) in Google Scholar

Description

Phosal 50 PG is a cosolvent (standardised phosphatidylcholine concentrate). Phosal 50 PG as a carrier for lipophilic compounds, can improve the absorption, efficacy and therapeutic index of the active ingredient[1].

In Vivo

Phosal 50 PG is usually used as a cosolvent.
Navitoclax (HY-10087) (100 mg/kg, once a day for 21 days) is formulated in 10% ethanol, 30% polyethylene glycol 400, and 60% Phosal 50 PG and administered p.o. to mice[2].
A-1331852 (HY-19741) (25 mg/kg, daily for 10 days) is formulated in 2.5% DMSO, 10% ethanol, 27.5% PEG 300, and 60% Phosal 50 PG and administered p.o. to mice[3].
Venetoclax (HY-15531) (100 mg/kg, daily for 10 days) is formulated in 10% ethanol, 30% PEG 400, 60% Phosal 50 PG and administered p.o. to mice[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.

774594-96-6

Appearance

Liquid (Density: 0.982 g/cm3)

Color

Light yellow to yellow

SMILES

[Phosal 50 PG]

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, protect from light

Pureté et documentation

Références
  • [1]. Khani S, et al. Improved oral bioavalability of mebudipine upon administration in PhytoSolve and Phosal-based formulation (PBF). AAPS PharmSciTech. 2014 Feb;15(1):96-102.  [Content Brief]

  • [1]. Khani S, et al. Improved oral bioavalability of mebudipine upon administration in PhytoSolve and Phosal-based formulation (PBF). AAPS PharmSciTech. 2014 Feb;15(1):96-102.

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Phosal 50 PG Related Classifications

  • Others
  • Others
  • Biochemical Assay Reagents
  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phosal 50 PG774594-96-6Biochemical Assay Reagentslipophilic compoundsabsorptionefficacytherapeutic indexphosphatidylcholineInhibitorinhibitorinhibit

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