General Info
Applications: | ELISA |
Reactivity: | Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 5.9pg/mL |
Detection Limit: | 15.6-1000pg/mL |
Short Description: | This GPI Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Gpi |
Gene ID: | 292804 |
Uniprot ID: | G6PI_RAT |
Sample Type: | serum, plasma or other biological fluids. |
Description
Tissue Specificity | |
Post Translational Modifications | Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway. ISGylated. |
Function | In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
Protein Name | Glucose-6-Phosphate IsomeraseGpiAutocrine Motility FactorAmfNeuroleukinNlkPhosphoglucose IsomerasePgiPhosphohexose IsomerasePhi |
Database Links | Reactome: R-RNO-5628897Reactome: -RNO-6798695Reactome: -RNO-70171Reactome: -RNO-70263 |
Cellular Localisation | CytoplasmSecreted |
Alternative ELISA Names | Glucose-6-Phosphate Isomerase ELISA kitGpi ELISA kitAutocrine Motility Factor ELISA kitAmf ELISA kitNeuroleukin ELISA kitNlk ELISA kitPhosphoglucose Isomerase ELISA kitPgi ELISA kitPhosphohexose Isomerase ELISA kitPhi ELISA kitGpi ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance