STRO-1

Referência M2421-10Y-100ul

Tamanho : 100ul

Marca : US Biological

Solicitar mais informações

Contactar o distribuidor local :


Telefone : +1 850 650 7790


M2421-10Y STRO-1

Clone Type
Polyclonal
Host
mouse
Isotype
IgM
Grade
Ascites
Applications
FC IF
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.||STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors. ||Applications: |Suitable for use in Immunofluorescence and Flow Cytometry. Other applications not tested.||Recommended Dilutions:|Flow Cytometry: 1:25|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgM|Clone No: 7i35 (STRO-1)|Host: mouse|Concentration: Not Determined|Form: Supplied as a liquid.|Purity: Ascites|Immunogen: CD34+ bone marrow cells|Specificity: Recognizes a cell surface antigen expressed by bone marrow of human stromal cells and stromal precursors. Species Crossreactivity: primate||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
CD34+ bone marrow cells
Form
Supplied as a liquid.
Purity
Ascites
Specificity
Recognizes a cell surface antigen expressed by bone marrow of human stromal cells and stromal precursors. Species Crossreactivity: primate
References
1. Simmons, PJ and Torok-Storb, B (1991) Blood, 78: 55-62. 2. Simmons, PJ and Torok-Storb, B. (1991) Blood, 78: 2848-2853.