APAF1 Polyclonal Antibody, Biotin Conjugated
Referência bs-0058R-Biotin
Tamanho : 100ul
Marca : Bioss
APAF1 Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-0058R-Biotin |
Product Name | APAF1 Polyclonal Antibody, Biotin Conjugated |
Applications | WB, ELISA, IHC-P, IHC-F |
Reactivity | Human, Rat, Zebrafish |
Predicted Reactivity | Mouse, Dog, Horse |
Specifications | |
Conjugation | Biotin |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human Apaf-1 |
Immunogen Range | 1201-1248/1248 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Gene ID | 317 |
Swiss Prot | O14727 |
Subcellular location | Cytoplasm |
Synonyms | CED4; APAF-1; Apoptotic protease-activating factor 1; APAF1; KIAA0413 |
Background | Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |