Application ![]()
| WB, IP, IHC-P, E |
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Primary Accession | P14091 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 48 KDa |
Gene ID | 1510 |
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Other Names | Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | CTSE |
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Function | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. |
Cellular Location | Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome |
Tissue Location | Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes |