Dizocilpine
Referência M2646-10mg
Tamanho : 10mg
Marca : AbMole Bioscience
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Quality Control & Documentation
Biological Activity
Dizocilpine (MK-801) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
Chemical Information
| Molecular Weight | 221.3 |
| Formula | C16H15N |
| CAS Number | 77086-21-6 |
| Solubility (25°C) | DMSO 23 mg/mL |
| Storage | Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] K Harsha Vardhan Reddy, et al. Convergent Strategy to Dizocilpine MK-801 and Derivatives
[2] Peter Kovacic, et al. Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity
[3] T M Tzschentke, et al. Does the noncompetitive NMDA receptor antagonist dizocilpine (MK801) really block behavioural sensitization associated with repeated drug administration?
[4] L J Vanderschuren, et al. Dizocilpine (MK801): use or abuse?
[5] B Geter-Douglass, et al. Dizocilpine-like discriminative stimulus effects of competitive NMDA receptor antagonists in mice