FABP4 (Fatty Acid-binding Protein, Adipocyte, Adipocyte Lipid-binding Protein, ALBP, Adipocyte-type Fatty Acid-binding Protein, A-FABP, AFABP, Fatty Acid-binding Protein 4) (PE)

Referência 126551-PE-100ul

Tamanho : 100ul

Marca : US Biological

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126551-PE FABP4 (Fatty Acid-binding Protein, Adipocyte, Adipocyte Lipid-binding Protein, ALBP, Adipocyte-type Fatty Acid-binding Protein, A-FABP, AFABP, Fatty Acid-binding Protein 4) (PE)

Clone Type
Polyclonal
Host
rabbit
Source
human
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu
Accession #
NM_001442, NP_001433.1
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

Fatty acid binding proteins (FABPs) are proteins that reversibly bind fatty acids and other lipids. So far, nine tissue-specific cytoplasmic FABPs have been identified. Functions attributable to these lipid binding proteins remain unclear, but data are presented that indicate physiological roles in 1) fatty acid transport, esterification, and oxidation, 2) steroidogenesis, and 3) retinoid uptake, retinaldehyde reduction, and retinol esterification. Adipose tissue FABP (FABP4) binds both long chain fatty acids and retinoic acid. It delivers retinoic acid to nulear trans-acting proteins, thereby modulates genes coding for key proteins involved in lipid metabolism or differentiation. FABP4 is closely associated with metabolic syndrome, type 2 diabetes, and atheroscelerosis.||Applications:|Suitable for use in Western Blot. Other applications have not been tested.||Recommended Dilutions:|Optimal dilutions to be determined by the researcher.||Amino Acid Sequence:|MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As Reported |Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).|Purity: Purified by Protein A affinity chromatography.|Immunogen: Full length protein corresponding to aa1-132 from human FABP4.|Specificity: Recognizes human FABP4.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Full length protein corresponding to aa1-132 from human FABP4.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human FABP4.

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CSB-PA018424LC01HU-100ug
 100ug