FOSL1 Antibody - middle region : FITC
Referência ARP31377_P050-FITC
Tamanho : 100ul
Marca : Aviva Systems Biology
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FOSL1 Antibody - middle region (ARP31377_P050)
| Datasheets/Manuals | Printable datasheet for anti-FOSL1 (ARP31377_P050) antibody |
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| Publications | Seitz, O., Schürmann, C., Pfeilschifter, J., Frank, S. & Sader, R. Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes. J. Craniomaxillofac. Surg. 40, 379-86 (2012). 2184072721499227 |
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| Tested Species Reactivity | Human, Rat |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human FOSL1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 85%; Zebrafish: 85% |
| Peptide Sequence | Synthetic peptide located within the following region: TDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAK |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-FOSL1 (ARP31377_P050) antibody is Catalog # AAP31377 (Previous Catalog # AAPP02132) |
| Reference | Debinski,W. (2005) Mol. Cancer Res. 3 (4), 237-249 |
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| Gene Symbol | FOSL1 |
| Gene Full Name | FOS-like antigen 1 |
| Alias Symbols | FRA, FRA1, fra-1 |
| NCBI Gene Id | 8061 |
| Protein Name | Fos-related antigen 1 |
| Description of Target | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. |
| Uniprot ID | P15407 |
| Protein Accession # | NP_005429 |
| Nucleotide Accession # | NM_005438 |
| Protein Size (# AA) | 271 |
| Molecular Weight | 29kDa |
| Protein Interactions | NME7; CREB5; USF1; LDOC1; JUNB; MAFB; MAF; JUN; DDIT3; ATF2; CEBPG; CEBPE; CEBPA; ATF4; ATF3; PARVG; WFDC1; TAB2; ATXN1; MYC; KPNA1; PSMC3; EP300; CREBBP; TRIM24; UBC; HDAC1; CALCOCO1; ATF1; CREB1; SRF; ELK1; |
