Human ATP dependent metalloprotease YME1L1 (YME1L1) activation kit by CRISPRa
Referência GA107351
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Human ATP dependent metalloprotease YME1L1 (YME1L1) activation kit by CRISPRa
SKU
GA107351
YME1L1 CRISPRa kit - CRISPR gene activation of human YME1 like 1 ATPase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | YME1L1 |
| Locus ID | 10730 |
| Components | GA107351G1, ATP dependent metalloprotease YME1L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107351G2, ATP dependent metalloprotease YME1L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107351G3, ATP dependent metalloprotease YME1L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001253866, NM_014263, NM_139312, NM_139313 |
| UniProt ID | Q96TA2 |
| Synonyms | FTSH; MEG4; PAMP; YME1L |
| Summary | The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN401088 | YME1L1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.