Human IL-5 ELISpot Pair, 10 x 96-well
Referência EA101819
Tamanho : 10x96wells
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| Product Data | |
| ACCN | NM_000879 |
|---|---|
| Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
| Assay Type | Sandwich |
| Background | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013] |
| Components | ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples. |
| Cross Reactivity | No cross reactivity with other human cytokines |
| Format | 10 x 96-well |
| Gene Symbol | IL5 |
| Locus ID | 3567 |
| Signal | Colorimetric |
| Species | Human |
| Specificity | Recognizes both natural and recombinant human IL-5 |
| Target Symbol | IL5 |
| Description | Human IL-5 ELISpot Pair, 10 x 96-well |
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