Specifications

Product Data
Format	1 x 96-well (pre-coated plate)
Assay Type	Enzyme-Linked ImmunoSpot (ELISpot)
Assay Length	3h after cell stimulation
Signal	Colorimetric
Specificity	Recognizes natural human IL-6
Cross Reactivity	No cross reactivity with other human cytokines. No interference with soluble receptor gp80.
Components	Pre-coated ELISpot kits include precoated PVDF plates, Detection antibody, Alkaline phosphatase conjugate, BSA, BCIP/NBT ready-to-use substrate buffer.
Background	This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
Gene Symbol	IL6
Gene ID	3569