IL-3 (F-6) P
Referência sc-398177 P
Tamanho : 100µg/0.5ml
Marca : Santa Cruz Biotechnology
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Telefone : +1 850 650 7790
Anticorps IL-3 (F-6): sc-398177
- L'Anticorps IL-3 (F-6) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 117-146 au niveau C-terminus de IL-3 d'origine mouse
- recommandé pour la détection de IL-3 d'origine mouse par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps IL-3 (F-6) pour des applications de WB. Ces réactifs sont maintenant proposés en kit avec l'anticorps IL-3 (F-6) ().
ACCÈS RAPIDE AUX LIENS
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Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL-3 has also been shown to protect mast cells from undergoing apoptosis. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific α subunit and a signal transducing β subunit common to the IL-3/IL-5/GM-CSF receptors. The carboxy terminus of the β subunit has been shown to be necessary for activation of the MAP kinase signaling pathway. Although the IL-3 receptor has no intrinsic kinase activity, stimulation with IL-3 leads to tyrosine phosphorylation of the JAK/Tyk 2 family member, JAK2, which in turn activates and causes nuclear translocation of Stat5a and Stat5b.
| Espèces | Nom du Gène | Gene ID | Localisation chromosomique | Numéro d'accession de l'isoforme (ARNm) | Numéro d'accès aux protéines | Numéro OMIM™ |
|---|---|---|---|---|---|---|
| Mouse | Il3 | Entrez Gene ID: 16187 | 11 B1.3 | NM_010556 | UniProt ID: P01586 | N/A |
L'anticorps IL-3 préféré est l'Anticorps IL-3 (G-1): sc-28342.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps IL-3 (F-6) | sc-398177 | 200 µg/ml | .00 | |||
IL-3 (F-6): m-IgG Fc BP-HRP Kit | sc-538385 | 200 µg Ab; 10 µg BP | .00 | |||
IL-3 (F-6): m-IgGκ BP-HRP Kit | sc-535991 | 200 µg Ab; 40 µg BP | .00 | |||
IL-3 (F-6): m-IgG2a BP-HRP Kit | sc-548285 | 200 µg Ab; 10 µg BP | .00 | |||
IL-3 (F-6) peptide neutralisant | sc-398177 P | 100 µg/0.5 ml | .00 |
What application is the blocking peptide sc-398177 P appropriate for?
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- REVIEWS, PRODUCT